동물영양생리및 단백체

1. 실험실 소개

본 연구실은 동물 영양과 대사에 대한 생리학적 메커니즘의 규명을 통하여 동물의 생산성 향상 및 고부가가치 동물성식품 생산에 기여함은 물론, 관련 분야의 학문 발전에 기여한다. 아울러 최신 오믹스 기술의 접목을 통하여 유전자 맞춤형 정밀사양시스템 개발, 온도스트레스 저감, 고품질 우육 생산 및 저탄소 후보 사료자원의 탐색에 관한 선도적인 연구 경쟁력을 강화하여 동물산업의 국제화 및 개방화 시대에 부응하는 미래지향적 글로벌 동물산업 분야 고급인력 양성에 기여한다.

This laboratory contributes to the improvement of animal productivity and the production of high-value animal’s products, as well as the development of related fields through the identification of physiological mechanisms for animal nutrition and metabolism. Through the combination of the latest omics technology, it will contribute to promoting advanced human resources in the future-oriented global animal industry by strengthening its competitiveness in developing gene-tailored precision, animal nutrition, heat stress reduction, high-quality beef production, and research on low-carbon feed resources.

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주요 연구 목표

소의 체내 생리적 지표 발굴 및 그 기능 연구
스트레스와 관련된 생리적 지표 발굴 및 활용
가축의 생산성과 관련된 영양 유전체학 동물 연구 접목
소의 건강과 웰빙을 향상시키는 친환경 기능성 사료 첨가제 개발 및 활용

2. 실험실원 소개

지도교수: 이홍구
연구교수: 이재성, Ghassemi Nejad Jalil
박사후연구원: 김원섭, 팽동교
박사과정: 조용호, 조장훈, 박현영, 박기연, 김응석
석사과정: 박진수, 선채형, 김학성, 이준희, 금상훈, Kamali Yves, 김재영, 이영복, 김민석, 윤영준, 류호균, 김보미, 임정우
학부과정: 김유래, 주문수
연구원: 정혜선

3. 수행 연구과제(최근 3년간)

2017.04. ~ 2019.12. 유단백 합성 필수아미노산 선정 및 이용성 증진을 위한 연구 – 농기평
2017.03 ~ 2020.02. 한우육의 근육내 지방분포도 개선을 위한 태아 및 출생기 Vitamin A 대사각인 연구 - 한국연구재단
2018.01 ~ 2019.12. 축종별 온습도지수(THI) chart 작성 및 계사 내부 THI 예측 모형 개발 – 농진청
2018.03. ~ 2020.08. (BK21+)글로벌 축산전문인력 양성팀 – 한국연구재단
2018.08. ~ 2019.07. 젖소의 유중 기능성 지방산 조성 변화의 이들의 반추위 내 작용기전 조사 연구 – 산업체
2018.12. ~ 2019.11. 비육우(한우)에 대한 온도 스트레스 상황별 NALT 급여 효능 평가 – 산업체
2019.11. ~ 2020.10. 원유 및 유제품 중 지방산 분서 용역 – 산업체
2020.01. ~ 현재 이상기상(더위지수)에 따른 가축의 대사생리 기반 피해량 조사 평가기술 개발 – 농진청
2020.01. ~ 현재 거세우 고온스트레스 저감을 위한 사육단계별 사양관리 기술 개발 – 농진청
2020.03. ~ 현재 한우육의 근육 및 근내지방분포도 개선을 위한 태아 및 송아지시기 비타민 A의 대사각인 연구 - 한국연구재단

4. 연구실 주요 실적

Peer-reviewed publications SCI(E) (155), Domestic (44)

J.R.V. Ronel, Jalil GN, Kim JE, Moon JO, Lee JS, and Lee HG. 2021. Supplementing with L-Tryptophan increases medium protein and alters expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells. International Journal of Molecular Sciences. 22, 2751:1-13.
Peng DQ, Smith SB, and Lee HG. 2021. Vitamin A regulates intramuscular adipose tissue and muscle development: promoting high-quality beef production. Journal of Animal Science and Biotechnology. 12(1):1-10.
Jo JH, Jalil GN, Peng DQ, Kim HR, Kim SH, and Lee HG. 2021. Characterization of short-term heat stress in Holstein dairy cows using altered indicators of metabolomics, blood parameters, milk microRNA-216 and characteristics. Animals. 11:722:1-20.
Peng DQ, Jo YH, Kim SJ, Kim NY, Jalil GN, and Lee HG. 2020. Oral vitamin A supplementation during neonatal stage enhances growth, pre-adipocyte, and muscle development in Korean native calves. Animal Feed Science and Technology. 268:1-10.
Kim TB, Lee JS, Kim NY, Jalil GN, and Lee HG. 2020. In vitro and in vivo studies of rumen-protected microencapsulated supplement comprising linseed oil, vitamin E, rosemary extract, and hydrogenated palm oil on rumen fermentation. Animals. 10(9): 1-16.
Choi YJ, Kim JJ, Lee HG, Park KK, Kwon HC, Na YJ, and Lee SR. 2020. Modeling methane potential yield and chemical composition of bedded pack barn cattle manure: Influence of cattle, season, growth stage, its retention time and particle. Journal of Material Cycles and Waste Management. 22:1006-1018.
Kim YB, Kim DH, Jeong SB, Lee JW, Kim TH, Lee HG, and Lee KY. Black soldier fly larvae oil as an alternative fat source in broiler nutrition. Poultry Science. 99(6):3133-3143.
Kim DH, Lee YK, Lee SD, Kim SH, Lee SR, Lee HG, and Lee KY. 2020. Changes in production parameters, egg qualities, fecal volatile fatty acids, nutrient digestibility, and plasma parameters in laying hens exposed to ambient temperature. Frontiers in Veterinary Science. 7, 412:1-11.
Kim WS, Nejad JG, Roh SG, and Lee HG. 2020. Heat-shock proteins gene expression in peripheral blood mononuclear cells as an indicator of heat stress in beef calves. Animals. 10, 895:1-11.
Kim WS, Nejad JG, Peng DQ, Jung US, Kim MJ, Jo YH, Jo JH, Lee JS, and Lee HG. 2020. Identification of heat shock protein gene expression in hair follicles as a novel indicator of heat stress in beef calves. 14(7):1502-1509.
Peng DQ, Kim SJ, and Lee HG. 2020. Metabolomics analyses to characterize metabolic alterations in Korean native calves by oral vitamin A supplementation. Scientific Reports. 15;10(1):1-8.
J. S. Lee., W. Priatno., J. G. Nejad., D. Q. Peng., J. S. Park., J. O. Moon., and H. G. Lee. 2019. Effect of Dietary Rumen-Protected L-Tryptophan Supplementation on Growth Performance, Blood Hematological and Biochemical Profiles, and Gene Expression in Korean Native Steers under Cold Environment. Animals 9, 1036:1-11.
D. H. Park., D. Kothari., K. M. Niu., S. G. Han., J. E. Yoon., H. G. Lee., and S. K. Kim. 2019. Effect of Fermented Medicinal Plants as Dietary Additives on Food Preference and Fecal Microbial Quality in Dogs. Animals 9, 690:1-17.
T. Wang., S. W. Jeon., U. S. Jung., M. J. Kim., and H. G. Lee. 2019. l-Lactate Dehydrogenase B Chain Associated with Milk Protein Content in Dairy Cows. Animals 9, 442:1-9.
J. S. Lee., N. Kacem., W. S. Kim., D. Q. Peng., Y. J. Kim., Y. G. Joung., C. H. Lee., and H. G. Lee. 2019. Effect of Saccharomyces boulardii Supplementation on Performance and Physiological Traits of Holstein Calves under Heat Stress Conditions. Animals 9, 510:1-10.
T. Wang., H. G. Lee., and Y. Zhen. 2018. Responses of MAC-T Cells to Inhibited Stearoyl-CoA Desaturase 1 during cis-9, trans-11 Conjugated Linoleic Acid Synthesis. Lipids 53(6):647-652.
Jeong CH, Cheng WN, Bae H, Lee KW, Han SM, Petriello MC, Lee HG, Seo HG, and Han SG. 2017. Bee Venom Decreases LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells. Journal of Microbiology and Biotechnology. 27(10):1827-1836.
Kim JE, Koh EK, Song SH, Sung JE, Lee HA, Lee HG, Choi YW, and Hwang DY. 2017. Effects of five candidate laxatives derived from Liriope platyphylla on the 5-HT receptor signaling pathway in three cell types present in the transverse colon. Molecular Medicine Reports. 15(1) 431-441.
Wang T, Lee SB, Hwang JH, Lim JN, Jung US, Kim MJ, Kang HS, Choi SH, Lee JS, Roh SG, and Lee HG. 2015. Proteomic Analysis Reveals PGAM1 Altering cis-9, trans-11 Conjugated Linoleic Acid Synthesis in Bovine Mammary Gland. Lipids 50(5):469-81
Wang T, Lim JN, Lee JS, Lee SB, Hwang JH, Jung US, Kim MJ, Hwang DY, Lee SR, Roh SG, and Lee HG. 2015. Effects of dietary trans-9 octadecenoic acid, trans-11 vaccenic acid and cis-9, trans-11 conjugated linoleic acid in mice. Molecular Medicine Reports 12(2):3200-6.

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